If you are looking for the latest news and information on SK Bioscience, you will find it here. Among the topics discussed here are the recent approval of SK’s SKYTyphoid vaccine, and the fact that SK’s recombinant protein vaccine technology is set to gain emergency use listing (EUL) by the World Health Organization (WHO). You’ll also discover that SK’s $300 million investment in research and development is paving the way to develop vaccines against SARS-CoV-2 and other Betacoronaviruses.
CEPI’s deep trust based on SK’s proven technology
The Coalition for Epidemic Preparedness Innovations (CEPI) and SK Bioscience are joining forces in the fight against pandemics. As part of its 5-year plan, CEPI is committed to developing broadly protective coronavirus vaccines. These technologies are essential for global health security. They are also important for averting millions of deaths and averting trillions of dollars in economic damage.
SK Bioscience is a South Korean biopharmaceutical company that specializes in vaccine development. Its R&D portfolio includes cell-culture based influenza, pneumococcal conjugate, typhoid conjugate, and human papillomavirus vaccines. In addition to its core focus on vaccines, the company has expanded its R&D portfolio to include anti-cancer and other important vaccines.
SK Bioscience has a global reputation for research and development. The organization is supported by the Bill and Melinda Gates Foundation, the Wellcome Fund, and other organisations. Currently, the company is preparing to develop a COVID-19 variant-proof vaccine. This vaccine candidate has the potential to be manufactured at scale at low cost, making it viable for use in both low- and middle-income countries.
CEPI’s $300 million programme to advance the development of vaccines for SARS-CoV-2 variants and other Betacoronaviruses
As a result of the SARS-CoV-2 variant’s global emergence, CEPI is preparing to develop all-in-one coronavirus vaccines that protect against multiple SARS-CoV-2 variants. This is a critical part of the pandemic preparedness plan. It aims to speed the development of vaccines to a hundred days, in order to give world governments the best chance to contain an outbreak and limit the emergence of potentially dangerous variants.
CEPI is one of the leading organizations developing all-in-one coronaviruses. With this funding, it is moving toward its 100 Days Mission, which is endorsed by the G7 and G20. The mission aims to prevent the emergence of dangerous variants and limit the global economic damage.
CEPI is committed to the principle of equitable access to vaccines. A new initiative will support the design and development of a novel vaccine filling solution, which will allow rapid delivery of vaccines in Africa.
SKYCovione(tm) based on recombinant protein vaccine technology
The first COVID-19 vaccine candidate, SKYCovione(tm), developed by South Korean company SK bioscience, was recently approved by the World Health Organization (WHO). This vaccine is based on recombinant protein vaccine technology, which has a proven track record of generating neutralizing antibodies.
SKYCovione(tm) was tested in a Phase III clinical trial with 4,037 adults over 18 months. It induced neutralizing antibody responses against the SARS-CoV-2 parental strain. In addition, the vaccine also elicited strong immune response in animals.
SKYCovione(tm) is a recombinant protein vaccine with an IgG1 linker, which is followed by RBD fusion with Acinetobacter phage coat protein. RBD has an Fc domain, which enhances the recognition of IgG1 by immune system cells.
In addition to the RBD fusion, the vaccine contains five immunogenic peptides, including an Acinetobacter phage coat protein, and two cytotoxic T-lymphocyte epitopes. Additionally, the vaccine contains a T4 fibritin and HA tag to enhance the detection by commercial HA antibodies.
SKYTyphoid vaccine to be supplied globally
SK Bioscience’s SKYTyphoid vaccine will be supplied globally next year. This is the Korean vaccine maker’s sixth vaccine and is expected to help reduce the burden of typhoid fever. It can be administered to infants aged 6 months to 2 years. In addition to typhoid, SK bioscience also manufactures chicken pox and herpes zoster vaccines.
SK bioscience and the International Vaccine Institute (IVI) have been working on a typhoid vaccine since 2013. Using their conjugate technology, they developed a vaccine that is safe and immunogenic. Their new typhoid conjugate vaccine provides a longer-lasting immune response and is particularly effective in children as young as six months.
The typhoid vaccine is derived from the Salmonella typhi strain C6524, which is a highly virulent bacteria that is capable of spreading throughout the body. Once it is present in the body, it can be transmitted to other people through contaminated food and water. Typhoid causes a fever that is accompanied by headache and other flu-like symptoms. However, the disease can be prevented with an antibiotic treatment, which can reduce case fatality rates to less than 1%.
SKYCovione(tm) to be approved for emergency use listing (EUL) by the World Health Organization
If you’ve been following the news, then you know that last week, SK bioscience launched its first commercially available COVID-19 vaccine. With its patent pending nanoparticle technology, the company has been able to successfully deliver the SARS-CoV-2 Spike protein in a novel two-component system. The result is a vaccine that is both safe and effective, making it a good fit for low-income settings.
Fortunately, SK bioscience is not alone in its quest to make a dent in the world of vaccines. In fact, it has collaborated with a number of global health regulatory bodies in its efforts to develop and manufacture safe and effective vaccines. It has also submitted a request to the World Health Organization and European Medicines Agency for conditional use approvals. As a part of that effort, it has launched a distribution platform aptly named the Covax Facility.